Gold nanoparticles in chemo-, immuno-, and combined therapy: review [Invited]
Identifieur interne : 000790 ( Main/Exploration ); précédent : 000789; suivant : 000791Gold nanoparticles in chemo-, immuno-, and combined therapy: review [Invited]
Auteurs : L. A. Dykman [Russie] ; N. G. Khlebtsov [Russie]Source :
- Biomedical Optics Express [ 2156-7085 ] ; 2019.
Abstract
Functionalized gold nanoparticles (GNPs) with controlled geometrical and optical properties have been the subject of intense research and biomedical applications. This review summarizes recent data and topical problems in nanomedicine that are related to the use of variously sized, shaped, and structured GNPs. We focus on three topical fields in current nanomedicine: (1) use of GNP-based nanoplatforms for the targeted delivery of anticancer and antimicrobial drugs and of genes; (2) GNP-based cancer immunotherapy; and (3) combined chemo-, immuno-, and phototherapy. We present a summary of the available literature data and a short discussion of future work.
Url:
DOI: 10.1364/BOE.10.003152
PubMed: 31467774
PubMed Central: 6706047
Affiliations:
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Khlebtsov</name><affiliation wicri:level="1"><nlm:aff id="aff1">Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, 13 Prospekt Entuziastov, Saratov 410049,<country country="RU">Russia</country></nlm:aff><country xml:lang="fr">Russie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff2">Saratov National Research State University, 83 Ulitsa Astrakhanskaya, Saratov 410012,<country country="RU">Russia</country></nlm:aff><country xml:lang="fr">Russie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation><nlm:aff id="aff4"><email>khlebtsov_n@ibppm.ru</email></nlm:aff></affiliation></author></analytic><series><title level="j">Biomedical Optics Express</title><idno type="eISSN">2156-7085</idno><imprint><date when="2019">2019</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Functionalized gold nanoparticles (GNPs) with controlled geometrical and optical properties have been the subject of intense research and biomedical applications. 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